Hydrochlorothiazide? | Xerxes

Some days my mind gives me great words like ‘eudaimonia‘ or ‘matriculate’. Today, it decided to give me ‘hydrochlorothiazide’. You may think to yourself, “That sounds dangerous!”  I promise you; it’s not, unless you don’t need it.

hydrochlorothiazide_model
Hydrochlorothiazide

Anyone who has taken medicine for their high blood pressure and has had problems with fluid retention because of it will more than likely be acquainted with this magic little pill that makes your new night-time companion the toilet.  You got it folks, Hydrochlorothiazide is the chemical (functional molecule) in one of the most common treatments for sodium and fluid retention.

Hydrochlorothiazide is in a class of drugs called Thiazides used to treat high blood pressure and mild fluid retention.  It works by causing the kidneys to remove more sodium from the blood, in doing so, it also removes excess water, leading to a lower overall arterial pressure.

Hydrochlorothiazide has the chemical formula C7H8ClN3O4S2. Pictured above and to the right is its chemical model.  Pretty simple as far as medicines go.

Accompanying this weird word in my head this morning was the lovely tune from George Frideric Handel’s opera seria Xerxes, referred to simply by its tempo ‘Largo‘, and here voiced for organ and trumpet.



From CD Beauty and Power
Recorded in St. Peter & Paul Church in Kirchdorf, Switzerland.
Trumpet: Timothy Moke, Arizona
Pipe Organ: Georg Masanz, Switzerland
Organ Builder: Hauser, Switzerland
Trumpet: Selmer Piccolo Trumpet

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